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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7216e221dfa9bb2ea58354e6f4b062975c694000731101954a1fa409397a890' 
  AND token = 'cTqBrKQd9F7hbDIom/wpaqDI/hM8zFT52SjvMP08Ks8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}