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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44235426444c328188fe1e09da7974ad056687b1ce6ac1796d937364fe877c65' 
  AND token = 'DErZ+Vz8g+R+S84yfqrlDmfKJ98Zo0zEjT7rJruFmoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}