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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e856d25347e7f4de6cd3df2a256b3d65a1352f72729433357852066125431f4' 
  AND token = 'uTUWunQ7oXkzoe2IWArn0lggsTW1J43HOBh5C4oQBmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}