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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f8937bbb1cda601907708fc1a5ecf9b32d867d4cd90d690b97d4cd36fb0dff' 
  AND token = 'NATgIiteDxmNm2hqzgDt7A1/pBgSjjuYQvtMjQL3OCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}