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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118d86ce1519ecade72d973665fc0436a197937273ebe396de8bb42786cd4b21' 
  AND token = 'uWePP29UnkC3UJWImx5H53p44nFH4Sr6as3zd+8C3aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}