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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b92b46c4ffe3d7e9dcc34837ee044383dc89efc2480df48a2d72c9979a793a4' 
  AND token = 'CeMQYdnU7DsUdNnsoj0gOdUj8wU3t1CgjfdNMhh8SRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}