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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848300bd9474d1e6e1334593d2f2989eb57179024dc6d0480902db7d4b33b603' 
  AND token = '4TVuOlCPlY0PPTYtakdZWg8MveubnyMwEV+3s6qyHj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}