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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c74eafb4e6b3b987e74b286b8c2bd820f7af8449b87ac197c2b05824b51adf' 
  AND token = '2N/GntxIpVEyqpQn5BBTQhitGrqt/uToSq2FwUFNoSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}