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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e059348da19355abe09f97897e31ddc736b38856cf3fd87a442e0f0366691119' 
  AND token = 'mZdg2f49AxEuugy+2zg5j/QWhyU0MrNS3o2eJDA3rvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}