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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2103aee11ce505fb8cb5492762397703385718d889d62e8b1337b25842636136' 
  AND token = 'cRP2aWEyJEp103+OmpQMIkAbdpjcgbml2E3/QQAoPOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}