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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4bb32d070dc46616337ad00adb1217bce5b2059daaa91fa2d1e91ace35d635' 
  AND token = '8RSMe9H2RcSekVdxdjmlS3lItgw2wc56szT6v6t6PRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}