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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c239ef3c1072339f7de54344bdb1a4fa19974ad1eef672e1c46e53c408aa58' 
  AND token = 'Z2m6jYNlse8R08zusGbnDK4oSUGhmzIW8Z1JSP2+pP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}