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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db9a12de4ffebe67e21894fa6b7065941a030d4d813af2322090fe762a661fc4' 
  AND token = 'iU5tmOjDr2yW8AxmdzEPeFORWIWB9GwUfLHTkzZdCb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}