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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d73315a83533e0a396866fb02f0d242f2f9c4c9d15bac038b63b7d42bd5a30' 
  AND token = '3VQ5+Vg7o00222TKhMgOr1VPdHcsQEd1kT/ijXkFDqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}