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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d7d504132fd5fe879d0809ead06f455e53ffc09ff40efea1182d03e0934b3c' 
  AND token = 'xwGf5C+V6puJkWX7p75ISS0jpRQ1p/vi4jf5RVCuWSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}