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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc381ab13ec17cde233a6ea6cec8101a09144a3f64ad125473d753db32c6d58f' 
  AND token = 'NeUS2yJVeKXdOuBKbwsZ32b44cK3iFuV8GEH3dYyeG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}