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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e235f246cc6d4e5f025f504bdf268355ba3d076b0aca28ee8f77412c4472ab' 
  AND token = 'PQ34QR4CIXoofU7POYoe7YvvHWoD7rFoK85WUhterVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}