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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ad6cc46246d36715eede862c8203349b5f472da3d551f2318039c210216a96' 
  AND token = 'P9XaPRnVYYWWGThkLAQxv4uGV7e/5Pj48RO3p3X5Cu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}