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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0c5a5d6032456e3c587e6f12cfd8ba3325ff2086d29fa89e6fa0753c4608bcf' 
  AND token = 'XVpUb5R9QqIN5w3fh9MGRYPFaEUQkxvSCxiujpp3b9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}