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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04e57fee09ca7e67c0172a394680bba317fd0dc2dcbd4a086400b1ea1506b13' 
  AND token = 'Kwp5gqqTzQyqLrMfkt7He5WRbTX66nhBk/Z690kluCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}