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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80c72fd946614876ef79a112216f9320bac73259ea810ee14c58369d8fe9106' 
  AND token = 'loviZXzK6A0ZSvxFMS/ei9iu/jtJEz8ZO8JxHl7hnJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}