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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6cfc1331470eed54cf9f95dc68a64e21af9c281497c02955727eadac19ca2b' 
  AND token = '6kcNLUCQFKry3dkC2orPsPn5a+ExdpMj3ufz6aWv5ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}