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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0339f623c564464bcc6166d5d0758b3e7a78c123c6dc4a33fc60caf8df72e0b0' 
  AND token = 'nLsnKJRcf//Sjw4x9KiHBuSvK/Q9QpWQ2/uQYvu49rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}