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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b469a4f652a69aec49f312716683daea33a0af2b71d0e998c71917a541f5a81' 
  AND token = 'NPE3yG8naz4Cds7y+KujRC+y2sZpVuzK5lY6BdsRdqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}