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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81aa4282f34c1be2473176ed2d82bc5cb3afdb33f1012cbdb55a440e7f447557' 
  AND token = 'xKI75Ctr2TNUTt8yCy8TTLJ6oAvNV3g4FOoU6NIorOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}