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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57b192660fb90fb557115182b000cc17761f7c3cd13b6a0bb1b8f9fa4d2c517' 
  AND token = 'y5YFEO9RunLTAyx+xMxI37q8KMnWkLRKxsbBMBHV4no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}