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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c9c9ecfa21f11fe00a5c7c867a55fe6bb03873720e2eb528649ad10b12c4c5' 
  AND token = 'KY3fZ/31JJa27+b/qJLNnrfj4Quu8RIinTBUN1tmJ5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}