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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8647f0b8693b957de56729047c8890010b38b088091c8c4ab90dca2bfba9144c' 
  AND token = 'liK1kVYNrJLLTwAscUp8nHCWokEA+K5l0Ty/l+IFwNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}