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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0479b50e978edeb64776d152e2227da99f62be219458a0a38710287a47d8d3d3' 
  AND token = 'THg5r6WzMQb9g6fh/7+zAJ2/4OmRadoJe0tMFKIwtPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}