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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1472433ce0129bba6deff2cd25fecee37321e6c393d1d1973b337a49f079e1a3' 
  AND token = 'vsUS/W6RWTRxcxRFFa86WmcXZ8YOj+GDG0z5qlA/dy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}