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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c3d7d0cb726cf53bb9231149ce6b084e39cd9db9b1aa89e932813fc6709a3a' 
  AND token = 'VQgxN/QvjoI3XcOdE/79dueuiDCkxu86R7iDiMywhDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}