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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da374923d68d41c82b419ecbd2056599b13ca0c9b9775d51f46be903d21cda82' 
  AND token = 'MkmcuaBWYt2mwy6jAC7R3gir3swuc/bG7r99b5m7ckY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}