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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153e799a0536881fea18032a34e0843f8f3f8ee030cf65c2b3b0d33b2ce52410' 
  AND token = 'X5XKRkHuoruIfwbYQw1SYIdo3xAyKBbIzkVIQn9wSwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}