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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f53bb34a1101baaae54d65a55bf81bf4780259f2e41e0c0839fbec4d6fd8935' 
  AND token = 'UfXj6wgCR69RmHLrg4OkHpPKossTNnilQ2gTcHNHqDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}