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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2008bb370742a78e483f0a1d25b16d3b46d236cb4231eeaee56a3708cebc3f' 
  AND token = 'R4qSayR2h+N/PweLFxdBxwOMHId/qAx8nb26yvABy5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}