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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b586b8c1ede43a092e9f8b78b09a390c33f0e7bf96f96e4f86ff25a950a110' 
  AND token = 'v2b/Bxs1hnBthzkAXSw7aNerjyzyEmqX8juvopTw/Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}