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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae786a2bb575a7175b4a2d00e2bd265ba87273da7022fe4f13cac2e0388a0980' 
  AND token = 'GM5vbj+GMWy+7j10uvwWTPgWbcMb69htV9Ci7OhN15k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}