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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b366f4e764cdbb945b8eff4573526d4b7636dd5136899d281b3ea5689255323' 
  AND token = 'mlamrLFR+zIvk7uB7R9u5hZU7zFezeiEaS/k4+30rGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}