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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2197623a05405bff46dfcbc70c2f0f5ad73c352f53071caa3f345bb5bb46c9' 
  AND token = '+hzu3JMgS5Jvx7h+VhzltmW3x6ipeu0tcwZcxL47YI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}