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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745b71ef51cc8d86f9820483427eb48c98b7ddcbc015eca349afb88f76128628' 
  AND token = 'lP4jVMMP2GAWz136+6w2WDiMmzUWxWB+fuFdKyyzSB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}