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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f948f1b3c876812e05fa9ba3061fea65f226dd6d0a6a0c4caae478c62c37de8' 
  AND token = 'b13qjKf4dQJOdnrQyhgxiZg1QesE9fCLqx7rK3bPxCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}