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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f11c6402af68d302738bc89e00ca17fffa14be1a9a88629a8a86c287a79365' 
  AND token = 'qk0gp+aTJTr0gABBrrqsHbAF/v/tCwzM6Z3yWGPBCvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}