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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16204eeb8aa22223462f70e04ea557b8fbfe5fd0757098e3121d84c7bdc078f' 
  AND token = 'KG+cVDYx4vFEv0mFF96t9ATEHAzqSK1jSrbR84L6jPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}