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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df5d12381b547dfac56bbde1367717cb7304b0d2fd072b4ea9f2dd6998caba0' 
  AND token = 'zZFgmTudeebHOQyR0dO9+KUSdktVCM4oGQ10l5nA+QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}