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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac7ff5337597b153566a16e5eea3ff914467f5243b80660cb3e6017fd7c6d77' 
  AND token = 'PW0W04s1UT8wGmVKgEQ6jWBv3EoIPqpxonBtzAXH4WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}