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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb3fa2883b3095652eaf4cdf505a3e363877037f0b7a353ce8a5d2e8a61e448f' 
  AND token = 'vJvwO4piR+SA5kZVOiN+vTbutkqjBPnzr4Vbda+BvtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}