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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a60c2d277da4c48b38e7d0e46016cc06b4d0e097d913663478dde4008b7ab7' 
  AND token = 'sdOhxoLCI3SuWMhascE6QNiHbQ9f5t8t5nVljcd9XaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}