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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab8206920d5dbdcc97e24839bfc9f3332d6a40e99d631ae1b214f49680277d2' 
  AND token = '+AtUbYjUGrS6BL1LGyZWYY35p6YAKACHP4k0DG8Hooc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}