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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a9b6bc629a4309e647b19ed1f0399bca68a3a25234a86f96e014814950d4244' 
  AND token = '69KcZMjD6FYABm2etrxeV18707jF8hhQls3yaRCuW4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}