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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b35db9c69d2c7a9346b10f47e6b8c30f4e2043a1a1e3c986f305d6a3dc5ece27' 
  AND token = 'TSggjGPPl3VW/qE2RvEXpa3wjmr9j5jzMk3MdvCimxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}